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December 14, 2021

Genome Assembly of MRSA using Oxford Nanopore MinION Data

In this training you’re going to make an assembly of data produced by “Complete Genome Sequences of Eight Methicillin-Resistant Staphylococcus aureus Strains Isolated from Patients in Japan” from Hikichi et al. 2019 which describes: Methicillin-resistant Staphylococcus aureus (MRSA) is a major pathogen causing nosocomial infections, and the clinical manifestations of MRSA range from asymptomatic colonization of the nasal mucosa to soft tissue infection to fulminant invasive disease. Here, we report the complete genome sequences of eight MRSA strains isolated from patients in Japan. In this tutorial you will learn how to make a genome assembly by using Galaxy on ONT long read data.

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Bazante Sanders, Saskia Hiltemann, Helena Rasche

December 14, 2021

Genome Assembly of MRSA using Illumina MiSeq Data

In this training you’re going to make an assembly of data produced by “Complete Genome Sequences of Eight Methicillin-Resistant Staphylococcus aureus Strains Isolated from Patients in Japan” from Hikichi et al. 2019 which describes: Methicillin-resistant Staphylococcus aureus (MRSA) is a major pathogen causing nosocomial infections, and the clinical manifestations of MRSA range from asymptomatic colonization of the nasal mucosa to soft tissue infection to fulminant invasive disease. Here, we report the complete genome sequences of eight MRSA strains isolated from patients in Japan. In this tutorial you learn to use Galaxy to assemble and analyze the sequencing data from these strains.

Document

Bazante Sanders, Saskia Hiltemann, Helena Rasche

2017

Responsible innovation: From MOOC to book

This textbook is based on the MOOC Responsible Innovation offered by the TU Delft. It provides a framework to reflect on the ethics and risks of new technologies. How can we make sure that innovations do justice to social and ethical values? How can we minimize (unknown)risks? The book explains: • The concept and importance of responsible innovation for society • Key ethical concepts and considerations to analyse the risks of new technologies • Different types of innovation (e.g. radical, niche, incremental, frugal) • Roadmap for Responsible Innovation by Industry • The concept of Value Sensitive Design (VSD) It includes a link to all the web lectures as well as case studies ranging from care robots and nuclear energy to Artificial Intelligence and self-driving vehicles.

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Joost Groot Kormelink